Omar Alderete is expected to feature for Sunderland against Nottingham Forest on Friday after being forced off against Aston Villa because of illness.
The Paraguayan defender was withdrawn just after the hour mark and Le Bris revealed several in the squad, including Alderete, had been struggling with illness ahead of that game.
“Last week we had a few players unwell, which can happen,” he said.
“It is what it is, you have to manage the situation. For Omar, it was just that.
“It shows as well that on the bench now, we have more options. When they come on the pitch, they can influence the game.”
Meanwhile, Nilson Angulo and Betrand Traore are expected to return to partial training next week, while Jocelin Ta Bi has been back involved in the build up to Friday’s clash.
“Nilson and Bertrand are close to returning to part training next week and Jocelin has started the sessions with us this week so we might go further next week because he felt good which is good news,” Le Bris said.